246 Calef Highway, Barrington, NH 03825 603.664.7980


Single-use products offer many benefits over traditional stainless steel equipment, including flexibility, cost-effectiveness, and ease of use. They eliminate the need for cleaning and sterilization, which saves time and reduces the risk of contamination.

Purity One Sampling Solution

Streamlining Biopharmaceutical Manufacturing Processes with Single-Use Assemblies

Single-use technology is becoming more popular for bioprocessing and biomanufacturing due to its cost-reducing benefits. These benefits include the elimination of cleaning and validation requirements between batches, which saves both time and money. SU components also enhance efficiency by reducing sterilization time, increasing overall productivity, and decreasing downtime between batches. Additionally, they improve product quality by minimizing the risk of contamination and ensuring batch-to-batch consistency.

Single-use technology also facilitates the adoption of new bioprocessing techniques for improved yields and higher-quality products. As a result, it has become the preferred option for biopharmaceutical and biotech companies worldwide, as it provides flexibility, ease of use, and a competitive edge in a rapidly evolving industry.

Connect with a Casella team member to discuss your single-use needs!

Our Products Include:

Purity One Sampling Solution
Pharma Tubing
CPC Connectors
Malema Single Use Instrumentation

Custom Single-Use Assemblies

Tubing & Fittings

Aseptic Connections & Disconnections



2D & 3D Single-Use Bags

Purity One™ products are designed for use in biopharmaceutical manufacturing and are made of high-quality materials that meet industry standards for purity and biocompatibility.
Purity One™ single-use bags and assemblies are used in a variety of applications, including sampling, filtration, filling, transfer and storage. They are available in various sizes and configurations and can be customized to meet specific process requirements.

Available options include:

2D Bags available in 50mL – 50L with 1-4 port options.

3D Bags available in 50L – 2500L with up to 5 ports.

Purity One 2D & 3D Bags


Bottle Assemblies

Purity One™ bottles and flasks are engineered for aseptic fluid storage and handling applications. Manufactured in an ISO Class 7 Certified Cleanroom, Purity One’s bottle assemblies are constructed from USP <88> Class VI, and ADI-Free Components.

Available in standard volumes ranging from 30mL – 2,000mL in 2-3 port configurations, our bottles are customizable with either TPE or silicone tubing and bottle closures and can be gamma irradiated to a SAL assurance level of 10-6.

Available options include:

Square bottles available in 30mL – 200mL

Erlenmeyer flasks available in 125mL – 2000mL

Carboys available in 5L – 40L

Purity One Bottle Assemblies

Advantages of Single-Use Technology

Bioprocessing and biomanufacturing have increasingly favored single-use technology due to its numerous advantages. The primary benefit is cost reduction, as SU components do not require cleaning and validation between batches, which significantly reduces time and costs. Additionally, the need for costly equipment installations and upgrades is eliminated, thus reducing capital expenditures.

Single-use technology enhances efficiency by pre-sterilizing components, reducing sterilization time, and allowing for easy assembly and disassembly. This reduces downtime between batches and increases overall productivity. The quick switching of components also allows for greater manufacturing flexibility, reducing the time required for process changes and increasing the number of batches that can be run in a given time frame.

Single-use technology also enhances product quality by minimizing the risk of product contamination and ensuring batch-to-batch consistency. The disposable nature of SU components eliminates the risk of cross-contamination between batches, ensuring a high degree of product purity. Furthermore, single-use technology can facilitate the adoption of new and innovative bioprocessing techniques, allowing for improved yields and higher-quality products.

Overall, single-use technology has become the preferred option for biopharmaceutical and biotech companies worldwide. By reducing costs, improving efficiency, and enhancing product quality, single-use technology has quickly become a go-to option for bioprocessing and biomanufacturing. Its flexibility and ease of use allow for greater agility in manufacturing, making it a valuable tool for companies looking to stay competitive in a rapidly evolving industry.

Our Trusted Partners

Customizing Your SU Assemblies: The Key Options for Aseptic Manufacturing

Unlock the possibilities of aseptic manufacturing by delving into the key options available for customizing single-use assemblies and optimizing your processes.

Revolutionizing Pharmaceutical Manufacturing: The Advantages of SU 2D & 3D Bag Assemblies

Explore the game-changing advantages of single-use 3D bag assemblies and how they are revolutionizing pharmaceutical manufacturing for increased efficiency, flexibility, and cost-effectiveness.

Sustainability in Manufacturing: How SU 2D & 3D Bags are Making a Difference

Discover the positive impact of single-use 2D bags in manufacturing as we explore how they contribute to sustainability efforts and revolutionize the industry. 

Speak with a Dedicated Casella Representative

Casella has developed an extensive product offering through partnerships with industry leading sanitary process manufacturers. With extensive experience in the industry, count on us to meet your needs while improving your facility’s operation and efficiency.